Otay Mesa Enrollment Center Global Entry Interview & Appointment Guide

No appointments available

The Otay Mesa Enrollment Center sits on the south side of the pedestrian bridge at the Otay Mesa Port of Entry, serving San Diego and nearby Chula Vista along the California-Mexico border. GPS can be unreliable getting here, so it's worth following the specific route below rather than trusting turn-by-turn directions blindly. Confirm the facility on Google Maps before you head over.

No available appointments at Otay Mesa Enrollment Center?

As one of the busiest enrollment centers on the California border, appointment slots here can be scarce relative to demand from the San Diego area. Rather than refreshing the Trusted Traveler Programs site by hand, savvy travelers set up Snapslot to send a real-time text the moment a cancellation opens up, so they can grab it before anyone else does.

Knowing the Global Entry Application Process

  • Submit Your Application: Create a Trusted Traveler Programs account and submit the Global Entry application with the fee.
  • Await Conditional Approval: CBP reviews your background before clearing you to schedule an interview.
  • Schedule Your Interview: This office doesn't accept walk-ins, so a confirmed slot is the only way in. If nothing is open, Snapslot can alert you the moment a cancellation appears.
  • Attend Your Interview: A CBP officer reviews your documents and travel history in person near the pedestrian bridge.
  • Await Final Approval: Most applicants hear back shortly after the interview.

Preparing for your interview

Bring proof of residency (mortgage statement, rental agreement, or utility bill), your driver's license, vehicle registration and proof of insurance, birth certificate, and a machine-readable entry document such as a U.S. passport. Original documents only; copies aren't accepted. If you've ever been arrested, bring court documents showing the disposition regardless of outcome. The interview is largely an honesty check, so answer plainly and dress professionally, as you would for any appointment with a federal officer.

Getting to your appointment

Parking at Otay Mesa Enrollment Center

Parking is available near Paseo De Las Américas and Via De La Amistad, or in any nearby open or paid public lot. Because construction has affected parking at times, check your interview confirmation for specific parking instructions before you go.

Taking Public Transit to Otay Mesa Enrollment Center

There's a transit stop near the enrollment center; check the San Diego MTS website for current routes if you're coming from Chula Vista or elsewhere without a car. GPS directions to the office itself can be unreliable, so from I-805 or I-5, take the 905 East exit, then exit onto Siempre Viva Road East (the last U.S. exit), and turn right onto Roll Drive at the corner gas station.

No available appointments?

Check the Trusted Traveler Programs site directly for openings, or let Snapslot watch it for you.

Skip the manual refreshing: Snapslot texts you the moment an Otay Mesa cancellation opens up.
8/16/2026

Otay Mesa

9725 Via De La Amistad

San Diego, CA 92154

Phone Number

Directions

"DO NOT USE GPS" instead from 805 or 5 north/south take 905 East. Exit on Siempre Viva Rd East (last USA Exit). Follow Siempre Viva Rd and make a right on Roll Drive (US Gas on Corner). "DO NOT USE GPS" Sí usted viene manejando del norte ó del sur por la autopista 805 ó 5, tome la salida a la autopista 905 hacia el Este. Salga a la derecha en la última salida de EEUU (last USA exit) que es Siempre Viva Rd East. Continúe hasta la gasolinera (US GAS) y dé vuelta a la derecha en Roll Drive.

Notes

This Enrollment Center DOES NOT accept walk-in appointments. Este Centro NO ACEPTA visitas sin cita previa. PLEASE MAKE SURE TO BRING WITH YOU: • Proof of residency (mortgage statements, rental agreement, and utility bills). • Driver license, vehicle registration, and proof of insurance. • Birth certificate. • Machine-readable entry document such as US passport, Resident Alien Card, any other foreign passport and visa required for entry. Original documents only, No copies will be accepted. • A notarized authorization letter to enroll vehicle belonging to company or another person (if applicable). • If you have ever been arrested, please bring court documents verifying the disposition of the arrest (s), regardless of the date of the arrest and the outcome. HAVE ALL PERTAINABLE DOCUMENTS READY ON HAND, NOT DOING SO CAN CAUSE FOR YOUR APPLICATION TO BE DENIED OR FOR YOU TO BE RESCHEDULED. WE APPRECIATE YOUR ATTENTION TO THIS MATTER. **FAVOR ASEGÚRESE DE TRAER CONSIGO: • Prueba de residencia (estados de cuenta de hipoteca, contrato de alquiler y facturas de servicios públicos). • Licencia de conducir, registro del vehículo y comprobante de seguro. • Certificado de nacimiento. • Documento de entrada legible por máquina, como pasaporte estadounidense, tarjeta de extranjero residente, cualquier otro pasaporte extranjero y visa requerida para ingresar. Solo documentos originales, no se aceptarán copias. • Una carta de autorización notariada para inscribir el vehículo perteneciente a la empresa u otra persona (si corresponde). • Si alguna vez ha sido arrestado, traiga documentos judiciales que verifiquen la disposición del arresto (s), independientemente de la fecha del arresto y el resultado. TENGA LOS DOCUMENTOS PERTINENTES A LA MANO, NO HACERLO PUEDE CAUSAR QUE SU SOLICITUD SEA DENEGADA O SU CITA REPROGRAMADA.